Graphic showing silhouettes of two individuals pointing at a constellation with a galaxy in the background. The constellation shows IBS symptoms: bloating, cramping, urgency, incontinence, frequency of bowel movement, diarrhea
Graphic showing silhouettes of two individuals pointing at a constellation with a galaxy in the background. The constellation shows IBS symptoms: bloating, cramping, urgency, incontinence, frequency of bowel movement, diarrhea

IBS-D:
A LIFE OF DISRUPTION
AND DISSATISFACTION

IBS-D comprises multiple symptoms, but it is identified clinically by its dominant features of diarrhea and abdominal pain. In addition, patients with IBS-D typically experience urgency, and bloating.1 Nearly half experience fecal incontinence.2 While patients strongly desire improved symptom management, they often don’t clearly communicate the full extent of their condition due to not understanding the connection between their constellation of symptoms and IBS-D. In addition to an open dialogue, the Bristol Stool Form Scale (BFSF) can be used to educate patients and help classify abnormal bowel movements.2

MILLIONS EXPERIENCE SYMPTOMS
NEARLY EVERY DAY BUT GO UNDIAGNOSED3*

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SYMPTOMS

IBS-D CONSTELLATION OF SYMPTOMS

Recurrent diarrhea and abdominal pain are main symptoms of IBS-D. However, people with IBS-D often experience other disruptive symptoms, including: 2,4,5

  • Loose watery stools/diarrhea
  • Cramping
  • Frequency of bowel movements
  • Urgency
  • Bloating
  • Loss of bowel control/fecal incontinence

Patient quote: I have problems with diarrhea and major cramps. I have been scared to leave my house and I don’t go very far from home due to the worry of IBS acting up.Patient quote: I have problems with diarrhea and major cramps. I have been scared to leave my house and I don’t go very far from home due to the worry of IBS acting up.Patient quote: I have problems with diarrhea and major cramps. I have been scared to leave my house and I don’t go very far from home due to the worry of IBS acting up.

IBS-D IS A NEVER-ENDING CYCLE OF DEVASTATING SYMPTOMS2

When patients with IBS-D were asked to rank their most bothersome and frequent symptoms, they responded:2

Graph of the most bothersome symptoms in adults with IBS-DGraph of the most bothersome symptoms in adults with IBS-DGraph of the most bothersome symptoms in adults with IBS-D
Graph of the symptoms that IBS-D patients suffer nearly every day.Graph of the symptoms that IBS-D patients suffer nearly every day.Graph of the symptoms that IBS-D patients suffer nearly every day.
Patient quote: The IBS-D problems have been getting much worse. I cannot do anything without the fear of having an accident. So many milestones in my life have been ruined for me because of my problems.
Patient quote: The IBS-D problems have been getting much worse. I cannot do anything without the fear of having an accident. So many milestones in my life have been ruined for me because of my problems.

IBS-D PATIENTS WANT APPROPRIATE TREATMENT1

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58% want a treatment that improves their quality of life

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>50% are dissatisfied with current treatments

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46% are willing to try anything to manage IBS

TREATMENT

Treatment of IBS-D requires a multidisciplinary approach. This may include changes in diet and exercise, stress management, and psychological treatment.9 Another important component of IBS-D treatment is medication, which may help with symptom management.

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Nonpharmacologic treatment9

  • Diet
  • Fiber
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Pharmacologic treatment10,11

  • Mixed opioid agonists/antagonists
  • Antidiarrheals
  • Bile salt sequestrants
  • Probiotics
  • Antibiotics
  • 5-HT3 antagonists
  • Prosecretory agents
  • Tricyclic antidepressants (TCAs)
  • Selective serotonin reuptake inhibitors (SSRIs)
Patient quote: IBS is my living hell. I hate it so much. I just don’t understand why something so horrible does not have a cure. I feel like nobody knows about it or cares about it and sees it as a simple complication that is manageable. Well, it’s simply not manageable. Something needs to be done to fix this horrible life...
Patient quote: IBS is my living hell. I hate it so much. I just don’t understand why something so horrible does not have a cure. I feel like nobody knows about it or cares about it and sees it as a simple complication that is manageable. Well, it’s simply not manageable. Something needs to be done to fix this horrible life...

IBS-D:
A DOWNWARD SPIRAL

For IBS-D patients, anxiety, fear, and embarrassment are constant companions to physical symptoms.1,2 Despite bearing the significant burden of diarrhea, abdominal pain and spasms, the majority of patients wait years to consult a physician about their symptoms.1,2 During a consult, patients may not be able to articulate the full spectrum of their symptoms. Patient education using validated tools can help patients to gain a better understanding of their condition and more clearly communicate their symptoms to their doctors.

SATELLITE RESOURCES FOR IBS

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An open dialogue with patients may help reduce treatment delays and improve quality of life. The resources here are designed to help start the conversation and help with patient education and counseling.

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